Diabetic Ketoacidosis (DKA) Explained Clearly Remastered – DKA Pathophysiology
Get clarity on DKA (diabetic ketoacidosis) with memorable illustrations from Dr. Seheult. See the DKA series free at This video is part of the “MedCram Remastered” series: A video we’ve re-edited & sped up to make learning even more efficient.
This is video 1 of 2 on diabetic ketoacidosis (pathophysiology and signs of diabetic ketoacidosis / DKA):
0:08 DKA stats
0:47 DKA – cellular anatomy
2:30 insulin function
3:19 diabetes mellitus type 1
3:26 diabetes mellitus type 2
4:48 ketone bodies (acetone, acetoacetate, b-hydroxybutyrate)
6:09 carboxylic acid
6:23 conjugate base (anion gap acidosis)
8:17 DKA review
8:57 diabetic ketoacidosis – hyperkalemia
9:37 diabetic ketoacidosis – dehydration
9:50 osmotic diuresis
10:27 diabetic ketoacidosis – potassium effects
11:04 diabetic ketoacidosis – Cr elevation / renal failure
11:30 anion gap metabolic acidosis
12:09 measuring ketone bodies (serum ketones, b-hydroxybutyrate)
Visit for part 2 of this course (on DKA treatment) and over 100 lectures. This is the home for ALL MedCram.com medical videos (many medical videos, medical lectures, and quizzes are not on YouTube).
Speaker: Roger Seheult, MD
Co-Founder of MedCram.com (
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
Visit for hundreds of clear & concise videos
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MedCram: Medical education topics explained clearly including: Respiratory lectures such as Asthma and COPD. Renal lectures on Acute Renal Failure and Adrenal Gland. Internal medicine videos on Oxygen Hemoglobin Dissociation Curve and Medical Acid Base. A growing library on critical care topics such as Shock, Diabetic Ketoacidosis (DKA), and Mechanical Ventilation. Cardiology videos on Hypertension, ECG / EKG Interpretation, and heart failure. VQ Mismatch and Hyponatremia lectures have been popular among medical students and physicians. The Pulmonary Function Tests (PFTs) videos and Ventilator-associated pneumonia bundles and lectures have been particularly popular with RTs. NPs and PAs have given great feedback on Pneumonia Treatment and Liver Function Tests among many others. Dr. Jacquet teaches our FAST exam tutorial & bedside ultrasound courses. Many nursing students have found the Asthma and shock lectures very helpful. We’re starting a new course series on clinical ultrasound/ultrasound medical imaging.
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Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical education and exam preparation purposes, and not intended to replace recommendations by your doctor or health care provider.