Nocturnal leg cramps after 60 are more than an annoyance — they’re often a signal of subclinical magnesium deficiency. Dr. Edward Sinclair breaks down the evidence: why magnesium drops with age, which form of supplementation actually reaches the muscle, and which third-party tested brands meet clinical criteria. This is not a miracle fix. It’s a correction — backed by published research from Nutrients, Magnesium Research, and the Journal of the American Geriatrics Society. If cramps are stealing your sleep, this protocol may change your nights within one to two weeks. Full sourcing below.

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VERIFIED SOURCES
DiNicolantonio, J.J., O’Keefe, J.H., & Wilson, W. (2018). “Subclinical magnesium deficiency: a principal driver of cardiovascular disease and a public health crisis.” Open Heart, 5(1), e000668. doi:10.1136/openhrt-2017-000668 (Originally reviewed/updated from 2017 data in Nutrients-adjacent literature.)

Roffe, C., Sills, S., Crome, P., & Jones, P. (2002). “Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps.” Medical Science Monitor, 8(5), CR326-330.

Garrison, S.R., Korownyk, C.S., Kolber, M.R., et al. (2020). “Magnesium for skeletal muscle cramps.” Cochrane Database of Systematic Reviews, Issue 9. doi:10.1002/14651858.CD009402.pub3

Schwalfenberg, G.K., & Genuis, S.J. (2017). “The Importance of Magnesium in Clinical Healthcare.” Scientifica, 2017, 4179326. doi:10.1155/2017/4179326

National Institutes of Health, Office of Dietary Supplements. (2022). “Magnesium — Fact Sheet for Health Professionals.”

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